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Furthermore, clones 14, 5a and 7 comprising the arginine for glycine substitution at position 96 and further comprising a substitution or substitutions of serine for threonine at position 103 and valine for glutamic acid at position 114; leucine for proline at position 159; or glutamine to histidine at position 188, respectively, have pronouncedly different activities.

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D’un point de vue scientifique, il est même probable que le meldonium, utilisé lors d’épreuves sportives, réduise les facultés physiques car il ralentit l’oxydation des acides gras.

En effet, il ne faut pas oublier que les génériques sont toujours produits bien après les médicaments originaux (en général 5 ou 10 ans, selon les brevets et les législations) et qu’ils bénéficient donc des progrès accomplis par la médecine entre-temps.

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